HLCL-61 hydrochloride for cell activation

Catalog number
B1209-25
Name
HLCL-61 hydrochloride for cell activation
Size
25 mg
Price
545.00 EUR
Supplier

Details

Description
HLCL-61 is a potent and selective PRMT5 (potent arginine methyltransferase 5) inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members. In vitro data shows HLCL-61 effectively inhibits symmetric arginine demethylation of histones H3 and H4 in AML samples. HLCL-61 treatment of cells showed decrease in cell vitality and effective in apoptosis promotion in MV-11 and THP-1 cells after 48 hours.
Peptide sequence
N/A
CAS number
586395-74-6 (free base).
Molecular weight
380.92
Category
Biochemicals
Other name
1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride
Molecular formula
C₂₃H₂₅ClN₂O
Physical appearance
Crystalline Solid
Supplied with
N/A
Is this a salt?
Yes
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO(>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Additional description
For cells, cell lines and tissues in culture till half confluency.