Actinomycin D for cell activation

Catalog number
1036-5MG
Name
Actinomycin D for cell activation
Size
5 mg
Price
148.00 EUR
Supplier

Details

Description
An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines (1).
Peptide sequence
N/A
CAS number
50-76-0
Molecular weight
1255.5
Category
Apoptosis Inducer
Other name
Actinomycin C1, Actinomycin IV, Dactinomycin
Molecular formula
C₆₂H₈₆N₁₂O₁₆
Physical appearance
Red-Orange Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
>98% by TLC
Reconstitute instructions
DMSO (20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.