10058-F4 for cell activation

Catalog number
2739-25
Name
10058-F4 for cell activation
Size
25 mg
Price
414.00 EUR
Supplier

Details

Description
10058-F4 is a c-Myc inhibitor that inhibits the c-Myc-Max associationn and function. It prevents the growth of fibroblasts in a c-Myc-dependent manner. Downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Induces cell cycle arrest, apoptosis and myeloid differentiation in human acute myeloid leukemia. 10058-F4 inhibits the MYCN/Max interaction leading to cell cycle arrest, apoptosis and neuronal differentiation in MYCN-amplified neuroblastoma cells.
Peptide sequence
N/A
CAS number
403811-55-2
Molecular weight
249.35
Category
Biochemicals
Other name
5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Molecular formula
C₁₂H₁₁NOS₂
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (60 mg/ml) or EtOH (20 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Additional description
For cells, cell lines and tissues in culture till half confluency.