2'-Deoxy-6-thioguanosine for cell activation

Catalog number
2828-25
Name
2'-Deoxy-6-thioguanosine for cell activation
Size
25 mg
Price
686.00 EUR
Supplier

Details

Description
6-Thio-dG induces telomere dysfunction in telomerase-positive human cancer cells and hTERT-expressing human fubroblasts, but not in telomerase-negative cells. Treatment with 6-thio-dG results in rapid cell death for a wide variety of cancer cells, whereas normal human fibroblasts and human colonic epithelial cells are mostly unaffected.
Peptide sequence
N/A
CAS number
789-61-7
Molecular weight
283.31
Category
Biochemicals
Other name
2'-Deoxy-6-thio-D-guanosine;6-Thio-2'-deoxyguanosine; 6-thio-DG
Molecular formula
C₁₀H₁₃N₅O₃S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
M
Is it cell-permeable?
yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO:H₂O (1:2) (50 mM)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Additional description
For cells, cell lines and tissues in culture till half confluency.