Cathepsin L, human recombinant

Catalog number
1135-100
Name
Cathepsin L, human recombinant
Size
100 μg
Price
806.00 EUR
Supplier

Details

Target
Cathepsin L
Background
Cathepsin L is a lysosomal protease that can be secreted from the cell and is implicated to play a role in protein degradation, arthritis, apoptosis, and cancer.
Concentration
0.5 mg/ml
Molecular weight
24.2 kDa (114-333 aa)
Synonym
Cathepsin
Other name
Cathepsin L1, Major excreted protein, Cathepsin U, Cathepsin V
NCBI gene number
1514
NCBI gene
CTSL1
Gene source
Human
NCBI number
P07711
Recombinant
Yes
Source
E. coli
Purification
≥90%
Tested applications
SDS-PAGE, HPLC
Level of endotoxin
N/A
Tested activity
> 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
Biological activity
> 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
Reesults
> 10000 mU/mg
Binding ability
N/A
Unit
1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5
Storage condition
-70°C
Shipping under
Dry ice
Physical appearance
Liquid
Physical properties
0.5 mg/ml in 25 mM Sodium Acetate, 50 mM NaCl, pH 5.5 containing 50% glycerol
How to reconstitute
N/A
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Gene
CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants