D4476 for cell activation

Catalog number
1770-1
Name
D4476 for cell activation
Size
1 mg
Price
137.00 EUR
Supplier

Details

Description
A cell-permeable, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC₅₀ = 0.3 µM). Also inhibits ALK5 (IC₅₀ = 0.5 µM) and p38ɑMAP kinase (IC₅₀ = 12 µM). Displays selectivity over many other protein kinases.
Peptide sequence
N/A
CAS number
301836-43-1
Molecular weight
398.41
Category
Biochemicals
Other name
4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
Molecular formula
C₂₃H₁₈N₄O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.