JM6 for cell activation

Catalog number
1913-5
Name
JM6 for cell activation
Size
5 mg
Price
170.00 EUR
Supplier

Details

Description
Cell-permeable. A slow-release prodrug version of Ro 61-8048 (Cat. No. 1912-5, 25), an inhibitor of KMO (kynurenine 3-monoxygenase), the enzyme that controls the kynurenine pathway, long believed to be implicated in neurodegeneration. JM6 reverses and prevents symptoms of neurodegenerative diseases like Alzheimer’s and Huntington’s in animal models. JM6 does not penetrate into the brain, but works by inhibiting KMO in the blood.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
518.61
Category
Biochemicals
Other name
2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-Nitrophenyl)-5-(Piperidin-1-yl)Methylthiazole
Molecular formula
C₂₃H₂₆N₄O₆S₂
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.