Spautin-1 for cell activation
Catalog number
2037-5
Name
Spautin-1 for cell activation
Size
5 mg
Price
208.00 EUR
Supplier
Details
Description
Cell-permeable. A specific and potent autophagy inhibitor in mammalian cells. It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes. Spautin-1 blocks the prosurvival autophagy pathway in cancer cells.
Peptide sequence
N/A
CAS number
1262888-28-7
Molecular weight
271.26
Category
Biochemicals
Other name
6-Fluoro-N-(4-fluorobenzyl)quinozaline-4-amine
Molecular formula
C₁₅H₁₁F₂N₃
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥97% by HPLC
Reconstitute instructions
DMSO (~ 100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
