Plumbagin for cell activation

Catalog number
2290-50
Name
Plumbagin for cell activation
Size
50 mg
Price
110.00 EUR
Supplier

Details

Description
A quinonoid constituent isolated from the root of Plumbago zeylanica. Displays anticarcinogenic, antiatherosclerotic, and antimicrobial effects as well as anticancer and antiproliferation properties in a variety of cell lines and animal models. Induces G2/M and autophagy in breast cancer cells by inhibiting Akt/mTOR pathway. Also potently inhibits histone acetyltransferase (HAT) activity in vivo. Plumbagin specifically inhibits p300-mediated acetylation of p53 but not the acetylation by p300/CREB-binding protein associated factor, PCAF, in vivo.
Peptide sequence
No
CAS number
481-42-5
Molecular weight
188.18
Category
Biochemicals
Other name
5-Hydroxy-2-methyl-1,4-naphthalened­ione
Molecular formula
C₁₁H₈O₃
Physical appearance
Orange red solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (~20 mg/ml) or EtOH (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.