Cercosporamide for cell activation

Catalog number
9662-100
Name
Cercosporamide for cell activation
Size
100 µg
Price
186.00 EUR
Supplier

Details

Description
Cercosporamide is a potent inhibitor of MAP-kinase interacting kinases (Mnk1 and Mnk2), and JAK3 (IC₅₀ values are 115, 11, and 31 nM for Mnk1, Mnk2 and JAK3, respectively). Also inhibits Pkc1. Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro.
Peptide sequence
N/A
CAS number
131436-22-1
Molecular weight
331.28
Category
Biochemicals
Other name
(9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide
Molecular formula
C₁₆H₁₃NO₇
Physical appearance
Yellow lyophilized solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95%
Reconstitute instructions
DMSO (~ 3 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.