anti-Hsp90 Antibody (Clone S88)

Catalog number
3098-100
Name
anti-Hsp90 Antibody (Clone S88)
Size
Hsp90 Antibody (Clone S88)
Price
425.00 EUR
Supplier

Details

Target of this antibody:
Hsp90
Alternative names of antibody target:
HSP90AA1, HSP90A, HSPCAL1 , HSPCAL4 , HSPN, HSP86, HSPCA, Hsp89, HSP90N, LAP2, HSPC1, FLJ31884
Background information:
Hsp90 (also known as Hsp82, Hsp83, or Hsp89), a 90 kDa protein, is the most abundant protein in the cytosolic fraction in many cell types. The high level of Hsp90 in many cell types sμggests that Hsp90 may play a general role in the cell, but little is known about its general function. Hsp90 has no known enzymatic activity, and thus it has been presumed that Hsp90 may function throμgh protein-protein interactions. Hsp90 exists in a dimeric form and has been observed to bind to several cellular proteins such as retro-virus kinases (PP60v-src), steroid receptors, heme-regulated protein kinase, actin and tubulin. In this regard, Hsp90, like Hsp70, may function as a “molecular chaperone”. Hsp90 exists as two isoforms referred to as Hsp86 and HSP84 in murine cells or Hsp90α and Hsp90β in human cells.
Antibody host:
Mouse
Clonality of antibody:
Monoclonal
Isotype:
Mouse IgG1
Clone:
S88
This antibody reacts with:
Human, mouse, rat, monkey, hamster, rabbit, bovine
Immunogene sequence:
Achlya ambisexualis Hsp90
Concentration of antibody:
0.2 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.2 mg/ml) in PBS containing 1 mg/ml BSA, 50% glycerol, and 0.2% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot, Immunoprecipitation, Immunofluorescence
Recommended usage:
Western blot analysis (1-2µg/ml), immunoprecipitation (4-8 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes a 90 kDa protein, corresponding to the apparent molecular weight of Hsp90 on SDS-PAGE immunoblots. This antibody detects both Hsp90 alpha and beta.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps