GSK-690693 for cell activation

Catalog number
2272-25
Name
GSK-690693 for cell activation
Size
25 mg
Price
577.00 EUR
Supplier

Details

Description
An ATP-competitive pan-Akt kinase inhibitor. Inhibits Akt kinase isoforms 1, 2, 3 with IC₅₀ values of 2, 13, and 9 nM, respectively. Inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity.
Peptide sequence
N/A
CAS number
937174-76-0
Molecular weight
425.48
Category
Biochemicals
Other name
4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)­-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[­4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
Molecular formula
C₂₁H₂₇N₇O₃
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~20 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Additional description
For cells, cell lines and tissues in culture till half confluency.