anti-Phospho (Ser19) Tyrosine Hydroxylase Antibody

Catalog number
anti-Phospho (Ser19) Tyrosine Hydroxylase Antibody
Phospho (Ser19) Tyrosine Hydroxylase Antibody
436.00 EUR


Target of this antibody:
Phospho (Ser19) THY
Alternative names of antibody target:
TH; TYH; Tyrosine hydroxylase
Background information:
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drμg abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004). The activity of TH is also regulated by phosphorylation (Haycock et al., 1982; Haycock et al., 1992; Jedynak et al., 2002). Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.
Antibody host:
Clonality of antibody:
Rabbit IgG
This antibody reacts with:
Mammalian, rat
Immunogene sequence:
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser19 of rat tyrosine hydroxylase.
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 μl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50% glycerol.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot, Immunoprecipitation, Immunofluorescence
Recommended usage:
The antibody can be used for Western blotting (1:1000), Immunofluorescence (1:1000) and Immunohistochemistry (1:1000). However, the optimal conditions should be determined individually.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation