anti-IGF-I Antibody

Catalog number
5119-100
Name
anti-IGF-I Antibody
Size
IGF-I Antibody
Price
316.00 EUR
Supplier

Details

Target of this antibody:
IGF-I
Alternative names of antibody target:
IGF1, IGF-1, IGF 1, Insulin like growth factor-1, Insulin like growth factor 1
Background information:
IGF-I (Insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. Human IGF-I is a 7.6 kDa protein containing 70 amino acid residues.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human
Immunogene sequence:
E. coli expressed human IGF-I
Concentration of antibody:
0.5 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-human IGF-I polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot, Neutralization, ELISA
Recommended usage:
Western blot analysis (0.5-4 µg/ml). Recombinant human IGF-I (Cat.# 4119-100) can be used as a positive control. Based on researchers feedback, the antibody can also be used in ELISA (2-3 µg/ml), and neutralization (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps