Active Human Calpain 1

Catalog number
1134-100
Name
Active Human Calpain 1
Size
100 μg
Price
490.00 EUR
Supplier

Details

Target
Calpain 1
Background
Ca²ᶧ-dependent cysteine proteinase with low Ca²ᶧrequirement (half maximal activation = 2 µM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.
Concentration
N/A
Molecular weight
112.0 kDa
Synonym
Calpain
Other name
Calcium-activated neutral proteinase 2, Short name=CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, Short name=M-calpain
NCBI gene number
823
NCBI gene
CAPN1
Gene source
Human
NCBI number
P07384
Recombinant
No
Source
Human Erythrocyte
Purification
≥95%
Tested applications
SDS-PAGE, HPLC
Level of endotoxin
N/A
Tested activity
>1000 units/mg protein
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
One unit is defined as the amount of enzyme that will hydrolyze one pmol Suc-LLVY-AMC per minute at 25 °C.
Storage condition
-70°C
Shipping under
gel pack
Physical appearance
Liquid
Physical properties
In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
How to reconstitute
N/A
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.