Adrenocorticotropic hormone, as its name implies, stimulates the adrenal cortex. More specifically, it stimulates secretion of glucocorticoids such as cortisol, and has little control over secretion of aldosterone, the other major steroid hormone from the adrenal cortex. Stimulates secretion of adrenal corticosteroids and induces growth of adrenal cortex. ACTH also called Tetracosactide directly activates G-proteins. A stimulator of adenylate cyclase and cAMP formation. Its molecular weight is 4.541 kDa.
Corticotropin-lipotropin, Pro-opiomelanocortin, POMC, ACTH, LPH, MSH, NPP, POC, CLIP, Tetracosactide.
Corticotropin-lipotropin, Pro-opiomelanocortin, POMC, ACTH, LPH, MSH, NPP, POC, CLIP, Tetracosactide, Adrenocorticotropin receptor, Melanocortin receptor 2
NCBI gene number
Level of endotoxin
Sterile filtered and lyophilized with no additives
How to reconstitute
Centrifuge the vial prior to opening. Reconstitute in sterile dW to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.
Centrifuge the vial prior to opening.
For Research Use Only! Not to be used in humans
Adrenocorticotropic hormone (ACTH), or corticotrophins.