Target of this antibody:
Alternative names of antibody target:
NIRF, URF2, RNF107, RP11472F14.2
This gene encodes a nuclear protein which is involved in cell cycle regulation. The encoded protein is a ubiquitin ligase capable of ubiquinating PCNP (PESTcontaining nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set and ring associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants, some of which are nonprotein coding. [Provided by RefSeq, Feb 2012].
Clonality of antibody:
This antibody reacts with:
Recombinant protein of human UHRF2
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
This antibody has been succesfully tested for use in following methods:
Western blot, Immunohistochemistry, Immunofluorescene
Western blot: 1:500 – 1:2000, IHC: 1:50 – 1:200, IF: 1:20 – 1:50.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.