(-)-JQ1 for cell activation

Catalog number
2384-1
Name
(-)-JQ1 for cell activation
Size
1 mg
Price
186.00 EUR
Supplier

Details

Description
Cell-permeable. A useful negative control for the BET bromodomain inhibitor (+)-JQ1 (Cat.No.2070). (−)-JQ1 enantiomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.
Peptide sequence
N/A
CAS number
1268524-71-5
Molecular weight
456.99
Category
Biochemicals
Other name
t-Butyl-2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Molecular formula
C₂₃H₂₅ClN₄O₂S
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20 ̊C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Additional description
For cells, cell lines and tissues in culture till half confluency.