CD40Ligand/TRAP, murine recombinant

Catalog number
4015-1000
Name
CD40Ligand/TRAP, murine recombinant
Size
1 mg
Price
3149.00 EUR
Supplier

Details

Target
CD40Ligand/TRAP
Background
CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant murine CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.
Concentration
N/A
Molecular weight
16.4 kDa
Synonym
CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L.
Other name
CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L.
NCBI gene number
21947
NCBI gene
CD40-L
Gene source
Mouse
NCBI number
P27548
Recombinant
Yes
Source
E. coli
Purification
≥98%
Tested applications
SDS-PAGE, HPLC
Tested activity
N/A
Biological activity
Determined by its ability to induce TNF-α and MIP-1α production by murine splenocytes. The expected ED₅₀ for this effect is
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized protein
Physical properties
Sterile filtered and then lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 0.1 M Arginine.
How to reconstitute
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Additional source
Recombinants or rec. proteins
Group
recombinants