2-Methyl-5-hydroxytryptamine hydrochloride for cell activation

Catalog number
2768-25
Name
2-Methyl-5-hydroxytryptamine hydrochloride for cell activation
Size
25 mg
Price
567.00 EUR
Supplier

Details

Description
2-Methyl-5-hydroxytryptamine is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). Recently, this has been used as one of the components of the chemical cocktails used for reprogramming of mouse somatic cells toward pluripotent cells in the absence of Oct4.
Peptide sequence
N/A
CAS number
845861-49-6
Molecular weight
226.71
Category
Biochemicals
Other name
3-(2-aminoethyl)-2-methyl-1H-indol-5-ol hydrochloride; 2-Me-5HT
Molecular formula
C₁₁H₁₄N₂O.HCl
Physical appearance
Beige solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥98% by HPLC
Reconstitute instructions
H₂O (>20 mg/ml)
Storage condition
RT
Shipping condition
RT
Maximum time for storage
36 months
Storage instructions
Protect from light and moisture
Additional description
For cells, cell lines and tissues in culture till half confluency. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,