Target of this antibody:
Alternative names of antibody target:
Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, TP2, TEAP
Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat, TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase (TERT or TP2). Telomerase expression is usually repressed in postnatal somatic cells resulting in shortening of telomeres. Overexpression of telomerase may be implicated with oncogenesis.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide surrounding amino acid 572 of human TP2.
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-TP2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
This antibody has been succesfully tested for use in following methods:
Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.