anti-Phospho-IRS (Ser616) Antibody (Clone HIR-B1)

Catalog number
3105-100
Name
anti-Phospho-IRS (Ser616) Antibody (Clone HIR-B1)
Size
Phospho-IRS (Ser616) Antibody (Clone HIR-B1)
Price
360.00 EUR
Supplier

Details

Target of this antibody:
Phospho-IRS
Alternative names of antibody target:
IRS, phospho-IRS, Phospho-IRS (Ser616)
Background information:
Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups.
Antibody host:
Mouse
Clonality of antibody:
Monoclonal
Isotype:
Mouse IgG1
Clone:
HIR-B1
This antibody reacts with:
Human
Immunogene sequence:
Synthetic peptide phosphorylated at Ser 616 site
Concentration of antibody:
1.0 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (1.0 mg/ml) purified mouse monoclonal antibody supplied in PBS with 0.05% (W/V) sodium azide.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Indirect ELISA, Western blot
Recommended usage:
The antibody can be used for indirect ELISA and WB.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps