Target of this antibody:
Alternative names of antibody target:
anti-TSC2, Tuberin, Tuberous sclerosis 2 protein homolog
TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor genes caused tuberous sclerosis complex (TSC), an autosomal dominant tumor syndrome. Tuberin is a product of the TSC2 tumor suppressor gene. Tuberin form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR).
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide surrounding amino acid 1548 of rat TSC2
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
200 µg (0.5 mg/ml) affinity purified rabbit anti-TSC2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 3962BP-50) is available separately.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.