anti-PAI-1 Antibody

Catalog number
5579-100
Name
anti-PAI-1 Antibody
Size
PAI-1 Antibody
Price
338.00 EUR
Supplier

Details

Target of this antibody:
PAI-1
Alternative names of antibody target:
PAI1, PAI 1, PAI, PAI-1, Plasminogen activator inhibitor , Endothelial plasminogen activator inhibitor
Background information:
PAI-1 (plasminogen activator inhibitor-1) is originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI-1 inhibits both tissue-type palsminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). High PAI-1 levels are associated with an increased risk of thromboembolic disease while PAI-1 deficiency may represent an inherited autosomal recessive bleeding disorder.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Rat
Immunogene sequence:
Recombinant rat PAI-1
Concentration of antibody:
0.5 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.5 mg/ml) protein A affinity purified rabbit anti-PAI-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 0.1% BSA, 0.02% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blot analysis (1-2 µg/ml). However, the optimal conditions should be determined individually. The antibody detects rat PAI-1. Cross reactivity of the antibody to other species has not been determined.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis
French translation
anticorps