(R,R)-Hymeglusin for cell activation

Catalog number
B1244-500
Name
(R,R)-Hymeglusin for cell activation
Size
500 µg
Price
295.00 EUR
Supplier

Details

Description
(R,R)-Hymeglusin is a specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. It is a fungal beta-lactone that inhibits mevalonate biosynthesis and is a good target for statins. It displays antimicrobial and anti-fungal activity.
Peptide sequence
N/A
CAS number
29066-42-0
Molecular weight
324.41
Category
Biochemicals
Other name
(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Molecular formula
C₁₈H₂₈O₅
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.