anti-Superoxide Dismutase 1 (SOD-1) Antibody

Catalog number
anti-Superoxide Dismutase 1 (SOD-1) Antibody
Superoxide Dismutase 1 (SOD-1) Antibody
147.00 EUR


Target of this antibody:
Alternative names of antibody target:
Superoxide Dismutase 1, SODC
Background information:
Superoxide Dismutase (SOD) is an oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. It belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occurring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. SOD1 destroys radicals which are normally produced within the cells and which are toxic to biological systems. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms.
Antibody host:
Clonality of antibody:
Rabbit IgG
This antibody reacts with:
Human, mouse, rat
Immunogene sequence:
Recombinant Human SOD1 (BV-M61)
Concentration of antibody:
0.5 mg/ml
Form of antibody:
Formulation of this antibody:
30 µg (0.5 mg/ml) of antibody in PBS containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification method:
Affinity Purified Antibody
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blot: 1:200
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation