Target of this antibody:
Alternative names of antibody target:
CRSP1, CRSP-1, Cofactor Required for Sp1 Transcriptional Activation 1, TRAP220, Thyroid Hormone Receptor-Associated Protein Complex Component, 220 kD, PPARBP, PPAR Binding Protein, DRIP205, Vitamin D Receptor Interacting Protein Complex Component, 205 kD, DRIP230, Vitamin D Receptor-Interacting Protein, 230 kD, TRIP2, Thyroid Receptor Interacting Protein 2, MED1, PBP, PPARGBP, RB18A
CSP1/TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Clonality of antibody:
This antibody reacts with:
Synthetic peptide between amino acid 1500 and 1600 of human CRSP1
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blot, Immunoprecipitation
Western blotting (1:500 – 1:2500 µg/ml), Immunoprecipitation. However, the optimal concentrations should be determined individually.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.