(R,R)-Hymeglusin for cell activation

Catalog number
B1244-1000
Name
(R,R)-Hymeglusin for cell activation
Size
1 mg
Price
480.00 EUR
Supplier

Details

Description
(R,R)-Hymeglusin is a specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. It is a fungal beta-lactone that inhibits mevalonate biosynthesis and is a good target for statins. It displays antimicrobial and anti-fungal activity.
Peptide sequence
N/A
CAS number
29066-42-0
Molecular weight
324.41
Category
Biochemicals
Other name
(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Molecular formula
C₁₈H₂₈O₅
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Additional description
For cells, cell lines and tissues in culture till half confluency.