Target of this antibody:
Alternative names of antibody target:
SYND1 , SYND 1 , SDC1 , CD138 , CD138 , CD 138 , Syndecan1 , Syndecan 1 , SDC
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat, hamster
Synthetic peptide surrounding amino acid 298 of human Syndecan-1
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-Syndecan-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
This antibody has been succesfully tested for use in following methods:
Western blotting (0.5-4 µg/ml), However, the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~100 kDa Syndecan-1 from samples of human, mouse, rat, and hamster origins. Cross-reactivity to other species has not been determined.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.