anti-EZH2 Antibody

EZH2

Enhancer of zeste homolog 2 (ENX-1), isoform CRA_b

Enhancer of zeste homolog 2 (Ezh2) is a member of the Polycomb group (PcG). The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. Enhancer of zeste homolog 2 (Ezh2) contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis.

Rabbit

Polyclonal

Rabbit IgG

Human, mouse, rat

Synthetic peptide mapping to the N-terminus of rat Ezh2

0.5 mg/ml

Liquid

100 µg (0.5 mg/ml) affinity purified rabbit anti- EZH2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.

Affinity purified

Western blot

Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3242BP-50) is available separately.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps