anti-IkBalpha Antibody

Catalog number
3252-100
Name
anti-IkBalpha Antibody
Size
IkBalpha Antibody
Price
316.00 EUR
Supplier
Biovision
Order

Details

Target of this antibody:
IkBalpha
Alternative names of antibody target:
NFKBIA, IKBA, MAD3,MAD-3, IkappaBalpha, I-kappa-B-alpha, # NFKBI, IkB-alpha, NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha
Background information:
IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-alpha undergoes phosphorylation at serine residues by an ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-kB then binds DNA and affects gene expression.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Mouse
Immunogene sequence:
E. coli expressed mouse IkBa
Concentration of antibody:
0.2 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.2 mg/ml) affinity-purified rabbit anti-IkB-alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blot (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Cross-reactivity to IkB-alpha of other species has not been determined.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps