anti-Caspase-6 Antibody

Catalog number

3256-100

Size

Caspase-6 Antibody

Price

316.00 EUR

Supplier

Biovision

Order

Details

Target of this antibody:

Caspase-6

Alternative names of antibody target:

CASP6, CASP-6 , MCH2

Background information:

Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.

Antibody host:

Rabbit

Clonality of antibody:

Polyclonal

Isotype:

Rabbit IgG

This antibody reacts with:

Human, mouse, rat

Immunogene sequence:

Synthetic peptide mapping to the C-terminus of rat caspase-6 large fragment

Concentration of antibody:

0.2 mg/ml

Form of antibody:

Liquid

Formulation of this antibody:

100 µg (0.2 mg/ml) rabbit anti-caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01 thimerosal.

Purification method:

Affinity purified

This antibody has been succesfully tested for use in following methods:

Western blot, Immunohistochemistry

Recommended usage:

Western blotting (0.5-4 µg/ml), and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100), mouse intestine (Cat.# 2601-100), and rat kidney (Cat. 2702-100) tissue lysate can be used as a positive controls. The antibody detects a full length (35 kDa) and the cleaved fragment (18 kDa) of caspase-6.

Storage information:

Shelf time: 12 months in temp.: -20 deg.C

Shipping conditions:

gel pack

How to handle this antibody:

The antibody solution should be gently mixed before use.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Properties

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps