anti-TreakR Antibody

TweakR

TNFSF12 , TWEAK , MGC20669 , MGC129581 , DR3LG ,

TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrates that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.

Rabbit

Polyclonal

Rabbit IgG

Human

E. coli expressed recombinant human Tweak

0.5 mg/ml

Liquid

100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human TWEAKR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Affinity purified

Western blot

Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps