anti-BAFF-R Polyclonal Antibody

BAFF-R

B Cell Activating Factor Receptor antibody,B-cell-activating factor receptor antibody,BAFF R antibody,BAFF receptor antibody,BAFF-R antibody,BAFFR antibody,BLyS receptor 3 antibody,BlySR3 antibody,BR 3 antibody,BR3 antibody,BROMIX antibody,CD 268 antibody,CD268 antibody,CD268 antigen antibody,CVID4 antibody,MGC138235 antibody,OTTHUMP00000028746 antibody,Prolixin antibody,TNFRSF 13C antibody,TNFRSF13C antibody,TR13C human antibody,Tumor Necrosis Factor Receptor Subunit Member 13C antibody,Tumor necrosis factor receptor superfamily member 13C antibody.

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFFR/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-κB and c-Jun N-terminal kinase.

Rabbit

Polyclonal

rabbit IgG

N/A

human, mouse, rat

Synthetic peptide mapping to the C-terminus of human BAFF-R

0.5 mg/ml

Liquid

100 μg (0.5 mg/ml) affinity purified rabbit anti-BAFF-R polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Affinity purified rabbit IgG

Western blot

Western blot: 1-4 µg

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Polyclonals and antibodies

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

anticorps