anti-Cathepsin K Antibody

Cathepsin K

CTSK , CTSO2 , CTSO , CTSO1, PKND, CTS02 , PYCD , MGC23107 , EC 3.4.22.38

Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin K expression is highest in bone, cartilage, and skeletal muscle.

Rabbit

Polyclonal

Rabbit IgG

Human, mouse, rat, chicken, rabbit, pig

Synthetic peptide surrounding amino acid 321 of rat cathepsin K

0.5 mg/ml

Liquid

100 µg (0.5 mg/ml) protein A purified rabbit anti-cathepsin K polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Affinity purified

Western blot, Immunoprecipitation, Immunohistochemistry

Western blotting (0.5-4 µg/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects proform (43 kDa) and the mature form (29 kDa) of cathepsin K.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.

anticorps