anti-SGLT-2 Antibody

SGLT-2

SGLT 2 , SGLT2 , SLC5A2 ,SLC5A 2 ,

Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolateral membranes by a facilitated sμgar transporter (GLUT). At least three members of SGLTs (SGLT 1-3) have been cloned and characterized. SGLTs transport a methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT-1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.

Rabbit

Polyclonal

Rabbit IgG

Human, mouse, rat

Synthetic peptide near the N-terminus of mouse SGLT-2

0.5 mg/ml

Liquid

100 µg (0.5 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Affinity purified

Western blot

Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects 74 kDa SGLT-2 from human, mouse, and rat origins. Reactivity to other species has not been determined. A ~55 kDa and a ~45 kDa bands can also been detected, representing the SGLT-2 cleavage fragments.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps