anti-TIF1a/TRIM24 Antibody

TRIM24/TIF1a

TF1A, TIF1, hTIF1, TIF1A, TIF1 Alpha, Transcriptional Intermediary Factor 1 Alpha, TRIM24, Tripartite Motif-Containing 24, RNF82, Ring Finger Protein 82, PTC6

TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.

Rabbit

Polyclonal

Rabbit IgG

Human, mouse

Synthetic peptide of human TIF1α/TRIM24

N/A

Liquid

100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Affinity purified

Western blot

Western blotting (1:500 – 1:2000). However, the optimal concentrations should be determined individually. HeLa cell lysate can be used as a positive control. The antibody recognizes the TIF1α/TRIM24 of human and mouse origins. Reactivity to other species has not been tested.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps