anti-MMP-2 Antibody

MMP-2

MMP2, MMP-2, MMP 2, Matrix metalloproteinase-2, Matrix metalloproteinase 2, Gelatinase A, TBE-1

The mammalian Matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a single peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contains the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.

Rabbit

Polyclonal

Rabbit IgG

rat

E. coli-expressed active rat 72-kDa type IV collagenase

0.5 mg/ml

Liquid

100 µg (0.5 mg/ml) affinity purified rabbit anti-rat MMP-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Affinity purified

Western blot, Immunoprecipitation

Western blot analysis (0.5-4 µg/ml) and immunoprecipitation (4-8 µg/ml). However, the optimal conditions should be determined individually. The antibody has no cross-reactivity with other MMP family members. Cross-reactivity to MMP-2 of other species has not been determined.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps