anti-Superoxide Dismutase 1 (SOD-1) Antibody (72B1)

Catalog number
6168-100
Name
anti-Superoxide Dismutase 1 (SOD-1) Antibody (72B1)
Size
Superoxide Dismutase 1 (SOD-1) Antibody (72B1)
Price
403.00 EUR
Supplier

Details

Target of this antibody:
SOD1
Alternative names of antibody target:
Superoxide dismutase, SOD1, SOD, ALS, ALS1, IPOA.
Background information:
Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. SOD1 destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Antibody host:
Mouse
Clonality of antibody:
Monoclonal
Isotype:
Mouse IgG 1
Clone:
72B1
This antibody reacts with:
Human
Immunogene sequence:
Recombinant human protein purified from E.coli
Concentration of antibody:
1 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
Purification method:
Ammonium sulphate precipitation purified antibody
This antibody has been succesfully tested for use in following methods:
Western blot, IP
Recommended usage:
Western blot: 1 µg/ml, IP: 1-2 µg.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps