GM-CSF, human recombinant

Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α

Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α, Colony-stimulating factor, Molgramostin, Sargramostim

A cytokine that stimulates the bone marrow to produce granulocytes and stem cells

GM-CSF

1437

CSF2

Human

P04141

Yes

E. coli

≥98%

N/A

The ED₅₀ determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 1 x 10⁷ units/mg.

14.6 kDa

-20°C

Gel pack

1 year

N/A

Lyophilized protein

Lyophilized from 10 mM Sodium Citrate, pH 3.5

Reconstitute in H₂O to a concentration of 0.1-1.0 µg/µl. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.

Centrifuge the vial prior to opening.

For Research Use Only! Not to be used in humans

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recombinants or rec. proteins

recombinants