IL-1 alpha, rat recombinant
Catalog number
4127-1000
Name
IL-1 alpha, rat recombinant
Size
1 mg
Price
5100.00 EUR
Supplier
Details
Synonyms
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Alternates names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Taglines
Activates TNF-α and plays a critical role in immune response regulation
Biomolecule/Target
IL-1 alpha
NCBI Gene ID #.
24493
NCBI Gene Symbol
IL1A
Gene Source
Rat
Accession #
P16598
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 2 x 10⁹ units/mg.
Molecular Weight
17.7 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and lyophilized from 1 mM Tris buffer, pH 8.0
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Description
The IL-1 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name
Rattus norvegicus
Additional source
Recombinants or rec. proteins
Group
recombinants
