anti-C-Kit/CD117 Antibody (NT)

Catalog number
6777-100
Name
anti-C-Kit/CD117 Antibody (NT)
Size
C-Kit/CD117 Antibody (NT)
Price
316.00 EUR
Supplier

Details

Target of this antibody:
c-Kit/CD117
Alternative names of antibody target:
KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
Background information:
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human.
Immunogene sequence:
This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT.
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification method:
N/A
This antibody has been succesfully tested for use in following methods:
Western blot, IHC, IF.
Recommended usage:
WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps