anti-L3MBTL1 polyclonal antibody

L3MBTL1

L3MBTL, L3MBT

L3MBTL1 is a member of the polycomb group (PcG) proteins, which function as transcriptional regulators in large protein complexes. In Drosophila, homozygous mutations in the L3MBTL1 gene have been demonstrated to cause brain tumors, identifying L3MBTL1 as a tumor suppressor gene. L3MBTL1 forms a homodimer and interacts with TEL (ETV6). L3MBTL1 probably plays a role in cell proliferation. Overexpression of L3MBTL1 induces multinucleated cells, suggesting that it is required for normal mitosis.

Rabbit

Polyclonal

Rabbit IgG

N/A

Human.

Polyclonal antibody raised in rabbit against human L3MBTL1 (lethal 3 malignant brain tumor-like protein), using the N-terminal part of the protein.

N/A

Liquid

In PBS with 0.05% sodium azide and 0.05% ProClin 300.

Protein G purified

Western blot, IP.

Western Blot: 1:1000, IP: 1 - 5 µg/IP

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Polyclonals and antibodies

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

anticorps