anti-HP1α, ß and γ polyclonal antibody

Catalog number
6861-25
Name
anti-HP1α, ß and γ polyclonal antibody
Size
HP1α, ß and γ polyclonal antibody
Price
349.00 EUR
Supplier
Biovision
Order

Details

Target of this antibody:
HP1α, ß and γ
Alternative names of antibody target:
CBX5, 1, 3
Background information:
HP1 alpha, beta and gamma are components of heterochromatin. They recognize and bind histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the inner nuclear membrane.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human, mouse.
Immunogene sequence:
Polyclonal antibody raised in rabbit against human HP1 β (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the α and γ isoforms.
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
In PBS with 0.05% sodium azide and 0.05% ProClin 300.
Purification method:
Protein G purified
This antibody has been succesfully tested for use in following methods:
Western blot, IF, ChIP.
Recommended usage:
Western Blot: 1:1000, IF: 1:500, ChIP: 4 µg/ChIP
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group
Polyclonals and antibodies
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation
anticorps