anti-BMI1 polyclonal antibody

BMI1

PCGF4, RNF51, FLVI2

BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.

Rabbit

Polyclonal

Rabbit IgG

N/A

Mouse.

Polyclonal antibody raised in rabbit against mouse BMI1 (BMI1 polycomb ring finger oncogene) using two KLH conjugated synthetic peptides containing a sequence from the central and the C-terminal region of the protein, respectively.

N/A

Liquid

In PBS with 0.05% (W/V) sodium azide.

Whole Anti-Sera

ELISA.

ELISA: 1:300.

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Polyclonals and antibodies

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

anticorps