anti-MUC1 Antibody (EP1024Y)

Catalog number
A1009-100
Name
anti-MUC1 Antibody (EP1024Y)
Size
MUC1 Antibody (EP1024Y)
Price
338.00 EUR
Supplier

Details

Target of this antibody:
MUC1
Alternative names of antibody target:
Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227
Background information:
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Antibody host:
Mouse
Clonality of antibody:
Monoclonal
Isotype:
Mouse IgG
Clone:
347CT26.1.3
This antibody reacts with:
Human
Immunogene sequence:
Purified His-tagged MUC1 protein (N-terminal fragment)
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
100 µl antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification method:
Affinity purified mouse IgG
This antibody has been succesfully tested for use in following methods:
Western Blot
Recommended usage:
Western Blot 1:1000; Immunohistochemistry 1:100 - 250
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps