anti-Phospho-Bcl-2 (Thr56) antibody

Catalog number
A1012-100
Name
anti-Phospho-Bcl-2 (Thr56) antibody
Size
Phospho-Bcl-2 (Thr56) antibody
Price
360.00 EUR
Supplier

Details

Target of this antibody:
Bcl-2 (Thr56)
Alternative names of antibody target:
BCL2; Apoptosis regulator Bcl-2
Background information:
The Bcl-2 family of proteins is the best characterized protein family involved in the regulation of apoptotic cell death in variety of cells. Bcl2 is an integral outer mitochondrial membrane protein that regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Mutation of Bcl-2 at Thr56 or S87 inhibits its anti-apoptotic activity during glucocorticoid-induced apoptosis of T lymphocytes.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human
Immunogene sequence:
Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Thr56
Concentration of antibody:
1mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 ug (1mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification method:
Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods:
WB, IHC, IP, IF, ELISA
Recommended usage:
WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; IF 1:200-1:1000; ELISA 1:20000
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps