anti-Phospho-Caspase-6 (Ser257) antibody

Caspase-6 (Ser257)

CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Caspases are the central components of the apoptotic response. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspases are divided into two classes: the initiator caspases, which include caspase 2, 8, 9 and 10 and the effector caspases, which include caspases 3, 6 and 7. Effector caspases being activated by initiator caspases leads the proteolytic cleavage of a broad spectrum of cellular targets, which ultimately leads to cell death.

Rabbit

Polyclonal

Rabbit IgG

N/A

Human, Mouse, Rat

Synthesized peptide derived from human Caspase-6 around the phosphorylation site of S257

1mg/ml

Liquid

100ug (1mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Affinity purified rabbit IgG

WB, IHC, IF, ELISA

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

anticorps