anti-AGTR2 Polyclonal Antibody

AGTR2

AGTR2 Antibody: AT2, ATGR2, MRX88, Type-2 angiotensin II receptor, Angiotensin II type-2 receptor, AT2

AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Rabbit

Polyclonal

Rabbit IgG

Human, Mouse, Rat

16 amino acid synthetic peptide from near the center of human AGTR2.

1 mg/ml

Liquid

50 µg (1mg/ml) of antibody in PBS containing 0.02% sodium azide.

affinity chromatography purified via peptide column.

WB, IHC, ELISA

WB-0.5 μg/mL, IHC-P-5 μg/mL, ELISA,

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Polyclonals and antibodies

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

anticorps