TPO, murine recombinant
Catalog number
4352-50
Name
TPO, murine recombinant
Size
50 μg
Price
664.00 EUR
Supplier
Details
Target
TPO
Background
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulation levels of platelets in vivo. The murine TPO is a soluble 18.7 kDa protein containing 174 amino acid residues, which comprises the receptor binding domain of the Mpl-ligand protein.
Concentration
N/A
Molecular weight
18.7 kDa
Synonym
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
Other name
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
NCBI gene number
21832
NCBI gene
TPO
Gene source
Mouse
NCBI number
P40226
Recombinant
Yes
Source
E. coli
Purification
≥98%
Tested applications
SDS-PAGE, HPLC
Tested activity
N/A
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human MO7e cells is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 10⁶ units/mg.
Reesults
< 1.0 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized protein
Physical properties
Sterile filtered and lyophilized from 10 mM Tris, pH 8.0
How to reconstitute
Reconstitute in H₂O to a concentration of 0.5-1.0 mg/ml. Further dilutions of this solution should be made into buffer containing carrier protein or medium containing serum. This solution can be stored at 4°C for 1 week or –20°C for future use.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Additional source
Recombinants or rec. proteins
Group
recombinants
